The Myosin Va Head Domain Binds to the Neurofilament-L Rod and Modulates Endoplasmic Reticulum (ER) Content and Distribution within Axons

The neurofilament light subunit (NF-L) binds to myosin Va (Myo Va) in neurons but the sites of interaction and functional significance are not clear. We show by deletion analysis that motor domain of Myo Va binds to the NF-L rod domain that forms the NF backbone. Loss of NF-L and Myo Va binding from...

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Detalles Bibliográficos
Autores principales: Rao, Mala V., Mohan, Panaiyur S., Kumar, Asok, Yuan, Aidong, Montagna, Lee, Campbell, Jabbar, Veeranna, Espreafico, Enilza M., Julien, Jean P., Nixon, Ralph A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040190/
https://www.ncbi.nlm.nih.gov/pubmed/21359212
http://dx.doi.org/10.1371/journal.pone.0017087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040190/
https://www.ncbi.nlm.nih.gov/pubmed/21359212
http://dx.doi.org/10.1371/journal.pone.0017087

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