Porcine Sialoadhesin (CD169/Siglec-1) Is an Endocytic Receptor that Allows Targeted Delivery of Toxins and Antigens to Macrophages

Sialoadhesin is exclusively expressed on specific subpopulations of macrophages. Since sialoadhesin-positive macrophages are involved in inflammatory autoimmune diseases, such as multiple sclerosis, and potentially in the generation of immune responses, targeted delivery of drugs, toxins or antigens...

Descripción completa

Detalles Bibliográficos
Autores principales: Delputte, Peter L., Van Gorp, Hanne, Favoreel, Herman W., Hoebeke, Inge, Delrue, Iris, Dewerchin, Hannah, Verdonck, Frank, Verhasselt, Bruno, Cox, Eric, Nauwynck, Hans J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040196/
https://www.ncbi.nlm.nih.gov/pubmed/21359217
http://dx.doi.org/10.1371/journal.pone.0016827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040196/
https://www.ncbi.nlm.nih.gov/pubmed/21359217
http://dx.doi.org/10.1371/journal.pone.0016827

Ejemplares similares