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Porcine Sialoadhesin (CD169/Siglec-1) Is an Endocytic Receptor that Allows Targeted Delivery of Toxins and Antigens to Macrophages

Sialoadhesin is exclusively expressed on specific subpopulations of macrophages. Since sialoadhesin-positive macrophages are involved in inflammatory autoimmune diseases, such as multiple sclerosis, and potentially in the generation of immune responses, targeted delivery of drugs, toxins or antigens...

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Detalles Bibliográficos
Autores principales:	Delputte, Peter L., Van Gorp, Hanne, Favoreel, Herman W., Hoebeke, Inge, Delrue, Iris, Dewerchin, Hannah, Verdonck, Frank, Verhasselt, Bruno, Cox, Eric, Nauwynck, Hans J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040196/ https://www.ncbi.nlm.nih.gov/pubmed/21359217 http://dx.doi.org/10.1371/journal.pone.0016827

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