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Prolonged Mechanical Ventilation Induces Cell Cycle Arrest in Newborn Rat Lung
RATIONALE: The molecular mechanism(s) by which mechanical ventilation disrupts alveolar development, a hallmark of bronchopulmonary dysplasia, is unknown. OBJECTIVE: To determine the effect of 24 h of mechanical ventilation on lung cell cycle regulators, cell proliferation and alveolar formation in...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040197/ https://www.ncbi.nlm.nih.gov/pubmed/21359218 http://dx.doi.org/10.1371/journal.pone.0016910 |