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Prolonged Mechanical Ventilation Induces Cell Cycle Arrest in Newborn Rat Lung

RATIONALE: The molecular mechanism(s) by which mechanical ventilation disrupts alveolar development, a hallmark of bronchopulmonary dysplasia, is unknown. OBJECTIVE: To determine the effect of 24 h of mechanical ventilation on lung cell cycle regulators, cell proliferation and alveolar formation in...

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Detalles Bibliográficos
Autores principales:	Kroon, Andreas A., Wang, Jinxia, Kavanagh, Brian, Huang, Zhen, Kuliszewski, Maciej, van Goudoever, Johannes B., Post, Martin
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040197/ https://www.ncbi.nlm.nih.gov/pubmed/21359218 http://dx.doi.org/10.1371/journal.pone.0016910

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