Circular Single-Stranded Synthetic DNA Delivery Vectors for MicroRNA

Single-stranded (ss) circular oligodeoxynucleotides were previously found to undergo rolling circle transcription (RCT) by phage and bacterial RNA polymerases (RNAPs) into tandemly repetitive RNA multimers. Here, we redesign them to encode minimal primary miRNA mimics, with the long term aim of intr...

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Detalles Bibliográficos
Autores principales: Seidl, Christine I., Ryan, Kevin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040211/
https://www.ncbi.nlm.nih.gov/pubmed/21359172
http://dx.doi.org/10.1371/journal.pone.0016925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040211/
https://www.ncbi.nlm.nih.gov/pubmed/21359172
http://dx.doi.org/10.1371/journal.pone.0016925

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