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Assessing Protein Immunogenicity with a Dendritic Cell Line-Derived Endolysosomal Degradome

BACKGROUND: The growing number of novel candidate molecules for the treatment of allergic diseases imposed a dramatic increase in the demand for animal experiments to select immunogenic vaccines, a pre-requisite for efficacy. Because no in vitro methods to predict the immunogenicity of a protein are...

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Detalles Bibliográficos
Autores principales: Egger, Matthias, Jürets, Alexander, Wallner, Michael, Briza, Peter, Ruzek, Silke, Hainzl, Stefan, Pichler, Ulrike, Kitzmüller, Claudia, Bohle, Barbara, Huber, Christian G., Ferreira, Fátima
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040223/
https://www.ncbi.nlm.nih.gov/pubmed/21359181
http://dx.doi.org/10.1371/journal.pone.0017278