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Assessing Protein Immunogenicity with a Dendritic Cell Line-Derived Endolysosomal Degradome
BACKGROUND: The growing number of novel candidate molecules for the treatment of allergic diseases imposed a dramatic increase in the demand for animal experiments to select immunogenic vaccines, a pre-requisite for efficacy. Because no in vitro methods to predict the immunogenicity of a protein are...
Autores principales: | Egger, Matthias, Jürets, Alexander, Wallner, Michael, Briza, Peter, Ruzek, Silke, Hainzl, Stefan, Pichler, Ulrike, Kitzmüller, Claudia, Bohle, Barbara, Huber, Christian G., Ferreira, Fátima |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040223/ https://www.ncbi.nlm.nih.gov/pubmed/21359181 http://dx.doi.org/10.1371/journal.pone.0017278 |
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