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Alterations of the retinoblastoma gene in metastatic breast cancer

Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, information about the potential role of RB1 mutations in breast cancer is...

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Detalles Bibliográficos
Autores principales: Berge, Elisabet Ognedal, Knappskog, Stian, Lillehaug, Johan Richard, Lønning, Per Eystein
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040352/
https://www.ncbi.nlm.nih.gov/pubmed/21253829
http://dx.doi.org/10.1007/s10585-011-9375-y