FKBP51 and Cyp40 are Positive Regulators of Androgen-dependent Prostate Cancer Cell Growth and the Targets of FK506 and Cyclosporin A

Prostate cancer (PCa) growth is dependent on androgens and the androgen receptor (AR), which acts by modulating gene transcription. Tetratricopeptide repeat (TPR) proteins (FKBP52, FKBP51 and Cyp40) interact with AR in PCa cells, suggesting roles in AR-mediated gene transcription and cell growth. We...

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Detalles Bibliográficos
Autores principales: Periyasamy, Sumudra, Hinds, Terry, Shemshedini, Lirim, Shou, Weinian, Sanchez, Edwin R.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040472/
https://www.ncbi.nlm.nih.gov/pubmed/20023700
http://dx.doi.org/10.1038/onc.2009.458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040472/
https://www.ncbi.nlm.nih.gov/pubmed/20023700
http://dx.doi.org/10.1038/onc.2009.458

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