Cargando…

FKBP51 and Cyp40 are Positive Regulators of Androgen-dependent Prostate Cancer Cell Growth and the Targets of FK506 and Cyclosporin A

Prostate cancer (PCa) growth is dependent on androgens and the androgen receptor (AR), which acts by modulating gene transcription. Tetratricopeptide repeat (TPR) proteins (FKBP52, FKBP51 and Cyp40) interact with AR in PCa cells, suggesting roles in AR-mediated gene transcription and cell growth. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Periyasamy, Sumudra, Hinds, Terry, Shemshedini, Lirim, Shou, Weinian, Sanchez, Edwin R.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040472/ https://www.ncbi.nlm.nih.gov/pubmed/20023700 http://dx.doi.org/10.1038/onc.2009.458

Ejemplares similares

Analysis of FK506, timcodar (VX-853) and FKBP51 and FKBP52 chaperones in control of glucocorticoid receptor activity and phosphorylation
por: Hinds, Terry D, et al.
Publicado: (2014)

Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52
por: Mustafi, Sourajit M., et al.
Publicado: (2014)

An improved reversibly dimerizing mutant of the FK506-binding protein FKBP
por: Barrero, Juan J., et al.
Publicado: (2016)

Association of job stress, FK506 binding protein 51 (FKBP5) gene polymorphisms and their interaction with sleep disturbance
por: Li, Peixin, et al.
Publicado: (2023)

Transient conformations in the unliganded FK506 binding domain of FKBP51 correspond to two distinct inhibitor-bound states
por: Anderson, Janet S., et al.
Publicado: (2023)

Analysing the visible conformational substates of the FK506-binding protein FKBP12
por: Mustafi, Sourajit M., et al.
Publicado: (2013)

Scaffold proteins of cancer signaling networks: The paradigm of FK506 binding protein 51 (FKBP51) supporting tumor intrinsic properties and immune escape
por: MARRONE, LAURA, et al.
Publicado: (2023)

Neuroprotective effects of Tacrolimus (FK-506) and Cyclosporin (CsA) in oxidative injury
por: Yousuf, Seema, et al.
Publicado: (2011)

Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6
por: Chen, Hui, et al.
Publicado: (2014)

Natural product ligands of FKBP12: Immunosuppressive antifungal agents FK506, rapamycin, and beyond
por: Rivera, Angela, et al.
Publicado: (2023)

FK506-binding protein 51 is a possible novel tumoral marker
por: Romano, S, et al.
Publicado: (2010)

The Emerging Role of Large Immunophilin FK506 Binding Protein 51 in Cancer
por: Romano, S, et al.
Publicado: (2011)

Effects of immunosuppressants, FK506 and cyclosporin A, on the osteogenic differentiation of rat mesenchymal stem cells
por: Byun, Yu-Kyung, et al.
Publicado: (2012)

FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential
por: Romano, S, et al.
Publicado: (2013)

Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12
por: Mustafi, Sourajit M., et al.
Publicado: (2014)

FK506 binding protein 5 (FKBP5) gene polymorphisms and their relationship with pharmacological response in bipolar disorders
por: Arnone, Danilo
Publicado: (2020)

FK506-binding protein 2 (FKBP13) inhibit Bax-induced apoptosis in Saccharomyces cerevisiae (yeast)
por: Akintade, Damilare D., et al.
Publicado: (2021)

Interactions of FK506 and Rapamycin With FK506 Binding Protein 12 in Opportunistic Human Fungal Pathogens
por: Vellanki, Sandeep, et al.
Publicado: (2020)

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy
por: Baida, Gleb, et al.
Publicado: (2018)

FK506 and Cyclosporin A Enhance IL-6 Production in Monocytes: A single-Cell Assay
por: Murayama, K., et al.
Publicado: (1994)

Circulating FK506 binding protein 51 mRNA expression in patients with pituitary adenomas
por: Yang, Yingying, et al.
Publicado: (2023)

Mitochondria–Nucleus Shuttling FK506-Binding Protein 51 Interacts with TRAF Proteins and Facilitates the RIG-I-Like Receptor-Mediated Expression of Type I IFN
por: Akiyama, Taishin, et al.
Publicado: (2014)

Identification of Tropoelastin as a Ligand for the 65-kD FK506-binding Protein, FKBP65, in the Secretory Pathway
por: Davis, Elaine C., et al.
Publicado: (1998)

Structural basis of nucleic acid recognition by FK506-binding protein 25 (FKBP25), a nuclear immunophilin
por: Prakash, Ajit, et al.
Publicado: (2016)

FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis
por: Knüppel, Larissa, et al.
Publicado: (2018)

Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents
por: Juvvadi, Praveen R., et al.
Publicado: (2019)

FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast
por: Sasaki, Mayuki, et al.
Publicado: (2022)

Maculopathy Associated with Tacrolimus (FK 506)
por: Koh, Taehyuk, et al.
Publicado: (2011)

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin
Publicado: (1992)

The FK506 binding protein 13 kDa (FKBP13) interacts with the C-chain of complement C1q
por: Neye, Holger, et al.
Publicado: (2004)

The effects of over-expression of the FK506-binding protein FKBP12.6 on K(+) currents in adult rabbit ventricular myocytes
por: Kettlewell, S., et al.
Publicado: (2009)

Tomato FK506 Binding Protein 12KD (FKBP12) Mediates the Interaction between Rapamycin and Target of Rapamycin (TOR)
por: Xiong, Fangjie, et al.
Publicado: (2016)

Association of SNPs in the FK-506 binding protein (FKBP5) gene among Han Chinese women with polycystic ovary syndrome
por: Ma, Xinyue, et al.
Publicado: (2022)

Rapamycin inhibits AR signaling pathway in prostate cancer by interacting with the FK1 domain of FKBP51
por: Zhang, Jing, et al.
Publicado: (2020)

FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells
por: Maeda, Keisuke, et al.
Publicado: (2021)

The Effect of FK 506 on the Reepithelialization of Superficial Skin Wound
por: Shin, Jeong Min, et al.
Publicado: (2017)

Androgen up-regulation of Twist1 gene expression is mediated by ETV1
por: Khatiwada, Prabesh, et al.
Publicado: (2020)

The 13-kD FK506 Binding Protein, FKBP13, Interacts with a Novel Homologue of the Erythrocyte Membrane Cytoskeletal Protein 4.1
por: Walensky, Loren D., et al.
Publicado: (1998)

Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain
por: Soontornniyomkij, Virawudh, et al.
Publicado: (2010)

Effects of FK506 on Ca(2+) Release Channels (Review)
por: Ozawa, Terutaka
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_guocu7kt42vhhirjqiehnoeplf