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A receptor fusion protein for the inhibition of murine oncostatin M

BACKGROUND: Most cytokines signal through heteromeric receptor complexes consisting of two or more different receptor subunits. Fusion proteins of the extracellular parts of receptor subunits turned out to be promising cytokine inhibitors useful in anti-cytokine therapy and cytokine research. RESULT...

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Detalles Bibliográficos
Autores principales: Brolund, Liv, Küster, Andrea, Korr, Sabrina, Vogt, Michael, Müller-Newen, Gerhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040522/
https://www.ncbi.nlm.nih.gov/pubmed/21223559
http://dx.doi.org/10.1186/1472-6750-11-3