Selective ERK Activation Differentiates Mouse and Human Tolerogenic Dendritic Cells, Expands Antigen-Specific Regulatory T Cells, and Suppresses Experimental Inflammatory Arthritis

OBJECTIVE: Most therapeutic treatments for autoimmune arthritis rely on immunosuppressive drugs, which have side effects. Although a previous study by our group showed that specific ERK activation suppressed immune responses, its application in a therapeutic setting has never been tested. The aim of...

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Detalles Bibliográficos
Autores principales: Arce, Frederick, Breckpot, Karine, Stephenson, Holly, Karwacz, Katarzyna, Ehrenstein, Michael R, Collins, Mary, Escors, David
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Experimental Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040564/
https://www.ncbi.nlm.nih.gov/pubmed/20967853
http://dx.doi.org/10.1002/art.30099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040564/
https://www.ncbi.nlm.nih.gov/pubmed/20967853
http://dx.doi.org/10.1002/art.30099

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