Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions

Axonally specific microtubule-associated protein tau is an important component of neurofibrillary tangles found in AD (Alzheimer's disease) and other tauopathy diseases such as CTE (chronic traumatic encephalopathy). Such tau aggregate is found to be hyperphosphorylated and often proteolyticall...

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Detalles Bibliográficos
Autores principales: Cheng Liu, Ming, Kobeissy, Firas, Zheng, Wenrong, Zhang, Zhiqun, Hayes, Ronald L, Wang, Kevin KW
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040574/
https://www.ncbi.nlm.nih.gov/pubmed/21359008
http://dx.doi.org/10.1042/AN20100012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040574/
https://www.ncbi.nlm.nih.gov/pubmed/21359008
http://dx.doi.org/10.1042/AN20100012

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