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Polymorphisms in Arsenic(+III Oxidation State) Methyltransferase (AS3MT) Predict Gene Expression of AS3MT as Well as Arsenic Metabolism

BACKGROUND: Arsenic (As) occurs as monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in humans, and the methylation pattern demonstrates large interindividual differences. The fraction of urinary MMA is a marker for susceptibility to As-related diseases. OBJECTIVES: We evaluated the impact...

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Detalles Bibliográficos
Autores principales: Engström, Karin, Vahter, Marie, Mlakar, Simona Jurkovic, Concha, Gabriela, Nermell, Barbro, Raqib, Rubhana, Cardozo, Alejandro, Broberg, Karin
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040604/
https://www.ncbi.nlm.nih.gov/pubmed/21247820
http://dx.doi.org/10.1289/ehp.1002471