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In Vivo Measurement of Brain GABA Concentrations by Magnetic Resonance Spectroscopy in Smelters Occupationally Exposed to Manganese

BACKGROUND: Exposure to excessive levels of manganese (Mn) is known to induce psychiatric and motor disorders, including parkinsonian symptoms. Therefore, finding a reliable means for early detection of Mn neurotoxicity is desirable. OBJECTIVES: Our goal was to determine whether in vivo brain levels...

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Detalles Bibliográficos
Autores principales: Dydak, Ulrike, Jiang, Yue-Ming, Long, Li-Ling, Zhu, He, Chen, Jian, Li, Wen-Mei, Edden, Richard A.E., Hu, Shuguang, Fu, Xue, Long, Zaiyang, Mo, Xue-An, Meier, Dieter, Harezlak, Jaroslaw, Aschner, Michael, Murdoch, James B., Zheng, Wei
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040609/
https://www.ncbi.nlm.nih.gov/pubmed/20876035
http://dx.doi.org/10.1289/ehp.1002192