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Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. Recent studies have greatly expanded the number of established SLE risk alleles, but the distribution of multiple risk alleles in cases versus controls and their relationship to subphenoty...

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Detalles Bibliográficos
Autores principales: Taylor, Kimberly E., Chung, Sharon A., Graham, Robert R., Ortmann, Ward A., Lee, Annette T., Langefeld, Carl D., Jacob, Chaim O., Kamboh, M. Ilyas, Alarcón-Riquelme, Marta E., Tsao, Betty P., Moser, Kathy L., Gaffney, Patrick M., Harley, John B., Petri, Michelle, Manzi, Susan, Gregersen, Peter K., Behrens, Timothy W., Criswell, Lindsey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040652/
https://www.ncbi.nlm.nih.gov/pubmed/21379322
http://dx.doi.org/10.1371/journal.pgen.1001311