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Effect of 1918 PB1-F2 Expression on Influenza A Virus Infection Kinetics

Relatively little is known about the viral factors contributing to the lethality of the 1918 pandemic, although its unparalleled virulence was likely due in part to the newly discovered PB1-F2 protein. This protein, while unnecessary for replication, increases apoptosis in monocytes, alters viral po...

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Detalles Bibliográficos
Autores principales: Smith, Amber M., Adler, Frederick R., McAuley, Julie L., Gutenkunst, Ryan N., Ribeiro, Ruy M., McCullers, Jonathan A., Perelson, Alan S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040654/
https://www.ncbi.nlm.nih.gov/pubmed/21379324
http://dx.doi.org/10.1371/journal.pcbi.1001081