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Expression of P. falciparum var Genes Involves Exchange of the Histone Variant H2A.Z at the Promoter

Plasmodium falciparum employs antigenic variation to evade the human immune response by switching the expression of different variant surface antigens encoded by the var gene family. Epigenetic mechanisms including histone modifications and sub-nuclear compartmentalization contribute to transcriptio...

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Detalles Bibliográficos
Autores principales: Petter, Michaela, Lee, Chin Chin, Byrne, Timothy J., Boysen, Katja E., Volz, Jennifer, Ralph, Stuart A., Cowman, Alan F., Brown, Graham V., Duffy, Michael F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040674/
https://www.ncbi.nlm.nih.gov/pubmed/21379342
http://dx.doi.org/10.1371/journal.ppat.1001292