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Expression of P. falciparum var Genes Involves Exchange of the Histone Variant H2A.Z at the Promoter
Plasmodium falciparum employs antigenic variation to evade the human immune response by switching the expression of different variant surface antigens encoded by the var gene family. Epigenetic mechanisms including histone modifications and sub-nuclear compartmentalization contribute to transcriptio...
Autores principales: | Petter, Michaela, Lee, Chin Chin, Byrne, Timothy J., Boysen, Katja E., Volz, Jennifer, Ralph, Stuart A., Cowman, Alan F., Brown, Graham V., Duffy, Michael F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040674/ https://www.ncbi.nlm.nih.gov/pubmed/21379342 http://dx.doi.org/10.1371/journal.ppat.1001292 |
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