Compensatory Evolution of pbp Mutations Restores the Fitness Cost Imposed by β-Lactam Resistance in Streptococcus pneumoniae

The prevalence of antibiotic resistance genes in pathogenic bacteria is a major challenge to treating many infectious diseases. The spread of these genes is driven by the strong selection imposed by the use of antibacterial drugs. However, in the absence of drug selection, antibiotic resistance gene...

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Detalles Bibliográficos
Autores principales: Albarracín Orio, Andrea G., Piñas, Germán E., Cortes, Paulo R., Cian, Melina B., Echenique, José
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040684/
https://www.ncbi.nlm.nih.gov/pubmed/21379570
http://dx.doi.org/10.1371/journal.ppat.1002000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040684/
https://www.ncbi.nlm.nih.gov/pubmed/21379570
http://dx.doi.org/10.1371/journal.ppat.1002000

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