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A unified framework for multi-locus association analysis of both common and rare variants

BACKGROUND: Common, complex diseases are hypothesized to result from a combination of common and rare genetic variants. We developed a unified framework for the joint association testing of both types of variants. Within the framework, we developed a union-intersection test suitable for genome-wide...

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Detalles Bibliográficos
Autores principales: Shriner, Daniel, Vaughan, Laura Kelly
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040731/
https://www.ncbi.nlm.nih.gov/pubmed/21281506
http://dx.doi.org/10.1186/1471-2164-12-89