Cargando…
A unified framework for multi-locus association analysis of both common and rare variants
BACKGROUND: Common, complex diseases are hypothesized to result from a combination of common and rare genetic variants. We developed a unified framework for the joint association testing of both types of variants. Within the framework, we developed a union-intersection test suitable for genome-wide...
Autores principales: | Shriner, Daniel, Vaughan, Laura Kelly |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040731/ https://www.ncbi.nlm.nih.gov/pubmed/21281506 http://dx.doi.org/10.1186/1471-2164-12-89 |
Ejemplares similares
-
Simultaneous Analysis of Common and Rare Variants in Complex Traits: Application to SNPs (SCARVAsnp)
por: Chen, Guanjie, et al.
Publicado: (2012) -
Both rare and common genetic variants contribute to autism in the Faroe Islands
por: Leblond, Claire S, et al.
Publicado: (2019) -
Enrichment analysis of genetic association in genes and pathways by aggregating signals from both rare and common variants
por: Yang, Wei, et al.
Publicado: (2011) -
Collapsing ROC approach for risk prediction research on both common and rare variants
por: Wei, Changshuai, et al.
Publicado: (2011) -
Multiple rare and common variants in APOB gene locus associated with oxidatively modified low-density lipoprotein levels
por: Khlebus, Eleonora, et al.
Publicado: (2019)