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Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes
BACKGROUND: Several approaches have been developed for miRNA target prediction, including methods that incorporate expression profiling. However the methods are still in need of improvements due to a high false discovery rate. So far, none of the methods have used independent component analysis (ICA...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040732/ https://www.ncbi.nlm.nih.gov/pubmed/21294859 http://dx.doi.org/10.1186/1471-2164-12-97 |