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Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes

BACKGROUND: Several approaches have been developed for miRNA target prediction, including methods that incorporate expression profiling. However the methods are still in need of improvements due to a high false discovery rate. So far, none of the methods have used independent component analysis (ICA...

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Detalles Bibliográficos
Autores principales: Bang-Berthelsen, Claus H, Pedersen, Lykke, Fløyel, Tina, Hagedorn, Peter H, Gylvin, Titus, Pociot, Flemming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040732/
https://www.ncbi.nlm.nih.gov/pubmed/21294859
http://dx.doi.org/10.1186/1471-2164-12-97