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Limited Transplantation of Antigen-Expressing Hematopoietic Stem Cells Induces Long-Lasting Cytotoxic T Cell Responses

Harnessing the ability of cytotoxic T lymphocytes (CTLs) to recognize and eradicate tumor or pathogen-infected cells is a critical goal of modern immune-based therapies. Although multiple immunization strategies efficiently induce high levels of antigen-specific CTLs, the initial increase is typical...

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Detalles Bibliográficos
Autores principales: Denning, Warren L., Xu, Jun, Guo, Siqi, Klug, Christopher A., Hel, Zdenek
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040734/
https://www.ncbi.nlm.nih.gov/pubmed/21379572
http://dx.doi.org/10.1371/journal.pone.0016897