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Limited Transplantation of Antigen-Expressing Hematopoietic Stem Cells Induces Long-Lasting Cytotoxic T Cell Responses
Harnessing the ability of cytotoxic T lymphocytes (CTLs) to recognize and eradicate tumor or pathogen-infected cells is a critical goal of modern immune-based therapies. Although multiple immunization strategies efficiently induce high levels of antigen-specific CTLs, the initial increase is typical...
Autores principales: | Denning, Warren L., Xu, Jun, Guo, Siqi, Klug, Christopher A., Hel, Zdenek |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040734/ https://www.ncbi.nlm.nih.gov/pubmed/21379572 http://dx.doi.org/10.1371/journal.pone.0016897 |
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