Human Cdc14B Promotes Progression through Mitosis by Dephosphorylating Cdc25 and Regulating Cdk1/Cyclin B Activity

Entry into and progression through mitosis depends on phosphorylation and dephosphorylation of key substrates. In yeast, the nucleolar phosphatase Cdc14 is pivotal for exit from mitosis counteracting Cdk1-dependent phosphorylations. Whether hCdc14B, the human homolog of yeast Cdc14, plays a similar...

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Detalles Bibliográficos
Autores principales: Tumurbaatar, Indra, Cizmecioglu, Onur, Hoffmann, Ingrid, Grummt, Ingrid, Voit, Renate
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040744/
https://www.ncbi.nlm.nih.gov/pubmed/21379580
http://dx.doi.org/10.1371/journal.pone.0014711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040744/
https://www.ncbi.nlm.nih.gov/pubmed/21379580
http://dx.doi.org/10.1371/journal.pone.0014711

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