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Sonic Hedgehog and Notch Signaling Can Cooperate to Regulate Neurogenic Divisions of Neocortical Progenitors

BACKGROUND: Hedgehog (Hh) signaling is crucial for the generation and maintenance of both embryonic and adult stem cells, thereby regulating development and tissue homeostasis. In the developing neocortex, Sonic Hedgehog (Shh) regulates neural progenitor cell proliferation. During neurogenesis, radi...

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Detalles Bibliográficos
Autores principales: Dave, Richa K., Ellis, Tammy, Toumpas, Melissa C., Robson, Jonathan P., Julian, Elaine, Adolphe, Christelle, Bartlett, Perry F., Cooper, Helen M., Reynolds, Brent A., Wainwright, Brandon J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040755/
https://www.ncbi.nlm.nih.gov/pubmed/21379383
http://dx.doi.org/10.1371/journal.pone.0014680