Secretion of Novel SEL1L Endogenous Variants Is Promoted by ER Stress/UPR via Endosomes and Shed Vesicles in Human Cancer Cells

We describe here two novel endogenous variants of the human endoplasmic reticulum (ER) cargo receptor SEL1LA, designated p38 and p28. Biochemical and RNA interference studies in tumorigenic and non-tumorigenic cells indicate that p38 and p28 are N-terminal, ER-anchorless and more stable relative to...

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Detalles Bibliográficos
Autores principales: Cattaneo, Monica, Lotti, Lavinia Vittoria, Martino, Simone, Alessio, Massimo, Conti, Antonio, Bachi, Angela, Mariani-Costantini, Renato, Biunno, Ida
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040770/
https://www.ncbi.nlm.nih.gov/pubmed/21359144
http://dx.doi.org/10.1371/journal.pone.0017206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040770/
https://www.ncbi.nlm.nih.gov/pubmed/21359144
http://dx.doi.org/10.1371/journal.pone.0017206

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