Substrate and product analogues as human O-GlcNAc transferase inhibitors

Protein glycosylation on serine/threonine residues with N-acetylglucosamine (O-GlcNAc) is a dynamic, inducible and abundant post-translational modification. It is thought to regulate many cellular processes and there are examples of interplay between O-GlcNAc and protein phosphorylation. In metazoa,...

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Detalles Bibliográficos
Autores principales: Dorfmueller, Helge C., Borodkin, Vladimir S., Blair, David E., Pathak, Shalini, Navratilova, Iva, van Aalten, Daan M. F.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040809/
https://www.ncbi.nlm.nih.gov/pubmed/20640461
http://dx.doi.org/10.1007/s00726-010-0688-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040809/
https://www.ncbi.nlm.nih.gov/pubmed/20640461
http://dx.doi.org/10.1007/s00726-010-0688-y

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