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Accelerated Insulin Pharmacokinetics and Improved Postprandial Glycemic Control in Patients With Type 1 Diabetes After Coadministration of Prandial Insulins With Hyaluronidase

OBJECTIVE: To compare the pharmacokinetics, pharmacodynamics, and safety of insulin lispro or regular human insulin (RHI) with or without recombinant human hyaluronidase (rHuPH20) administered before a standardized meal. RESEARCH DESIGN AND METHODS: In this four-way, crossover study, 22 patients wit...

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Detalles Bibliográficos
Autores principales: Hompesch, Marcus, Muchmore, Douglas B., Morrow, Linda, Vaughn, Daniel E.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041204/
https://www.ncbi.nlm.nih.gov/pubmed/21273493
http://dx.doi.org/10.2337/dc10-1892