Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that t...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Libertas Academica
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041236/ https://www.ncbi.nlm.nih.gov/pubmed/21344021 http://dx.doi.org/10.4137/CMC.S6507 |
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author | Ker, J. Du Toit-Prinsloo, L. Van Heerden, W.F.P. Saayman, G. |
author_facet | Ker, J. Du Toit-Prinsloo, L. Van Heerden, W.F.P. Saayman, G. |
author_sort | Ker, J. |
collection | PubMed |
description | Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculation at one end of the spectrum. The histological findings include areas of interstitial fibrosis. We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome. Histologically areas of subendocardial fibrosis was prominent and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome., with areas of subendocardial fibrosis as possible arrhythmogenic foci. |
format | Text |
id | pubmed-3041236 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-30412362011-02-22 Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? Ker, J. Du Toit-Prinsloo, L. Van Heerden, W.F.P. Saayman, G. Clin Med Insights Cardiol Case Report Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculation at one end of the spectrum. The histological findings include areas of interstitial fibrosis. We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome. Histologically areas of subendocardial fibrosis was prominent and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome., with areas of subendocardial fibrosis as possible arrhythmogenic foci. Libertas Academica 2011-02-02 /pmc/articles/PMC3041236/ /pubmed/21344021 http://dx.doi.org/10.4137/CMC.S6507 Text en © the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited. |
spellingShingle | Case Report Ker, J. Du Toit-Prinsloo, L. Van Heerden, W.F.P. Saayman, G. Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? |
title | Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? |
title_full | Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? |
title_fullStr | Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? |
title_full_unstemmed | Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? |
title_short | Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? |
title_sort | subendocardial fibrosis in left ventricular hypertrabeculation-cause or consequence? |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041236/ https://www.ncbi.nlm.nih.gov/pubmed/21344021 http://dx.doi.org/10.4137/CMC.S6507 |
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