Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?

Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that t...

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Autores principales: Ker, J., Du Toit-Prinsloo, L., Van Heerden, W.F.P., Saayman, G.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041236/
https://www.ncbi.nlm.nih.gov/pubmed/21344021
http://dx.doi.org/10.4137/CMC.S6507
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author Ker, J.
Du Toit-Prinsloo, L.
Van Heerden, W.F.P.
Saayman, G.
author_facet Ker, J.
Du Toit-Prinsloo, L.
Van Heerden, W.F.P.
Saayman, G.
author_sort Ker, J.
collection PubMed
description Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculation at one end of the spectrum. The histological findings include areas of interstitial fibrosis. We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome. Histologically areas of subendocardial fibrosis was prominent and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome., with areas of subendocardial fibrosis as possible arrhythmogenic foci.
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spelling pubmed-30412362011-02-22 Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence? Ker, J. Du Toit-Prinsloo, L. Van Heerden, W.F.P. Saayman, G. Clin Med Insights Cardiol Case Report Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculation at one end of the spectrum. The histological findings include areas of interstitial fibrosis. We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome. Histologically areas of subendocardial fibrosis was prominent and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome., with areas of subendocardial fibrosis as possible arrhythmogenic foci. Libertas Academica 2011-02-02 /pmc/articles/PMC3041236/ /pubmed/21344021 http://dx.doi.org/10.4137/CMC.S6507 Text en © the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
spellingShingle Case Report
Ker, J.
Du Toit-Prinsloo, L.
Van Heerden, W.F.P.
Saayman, G.
Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
title Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
title_full Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
title_fullStr Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
title_full_unstemmed Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
title_short Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
title_sort subendocardial fibrosis in left ventricular hypertrabeculation-cause or consequence?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041236/
https://www.ncbi.nlm.nih.gov/pubmed/21344021
http://dx.doi.org/10.4137/CMC.S6507
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