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Multiplex Target Enrichment Using DNA Indexing for Ultra-High Throughput SNP Detection

Screening large numbers of target regions in multiple DNA samples for sequence variation is an important application of next-generation sequencing but an efficient method to enrich the samples in parallel has yet to be reported. We describe an advanced method that combines DNA samples using indexes...

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Detalles Bibliográficos
Autores principales: Kenny, Elaine M., Cormican, Paul, Gilks, William P., Gates, Amy S., O'Dushlaine, Colm T., Pinto, Carlos, Corvin, Aiden P., Gill, Michael, Morris, Derek W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041504/
https://www.ncbi.nlm.nih.gov/pubmed/21163834
http://dx.doi.org/10.1093/dnares/dsq029