Biomolecular Systems of Disease Buried Across Multiple GWAS Unveiled by Information Theory and Ontology

A key challenge for genome-wide association studies (GWAS) is to understand how single nucleotide polymorphisms (SNPs) mechanistically underpin complex diseases. While this challenge has been addressed partially by Gene Ontology (GO) enrichment of large list of host genes of SNPs prioritized in GWAS...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Younghee, Li, Jianrong, Gamazon, Eric, Chen, James L., Tikhomirov, Anna, Cox, Nancy J., Lussier, Yves A.
Formato: Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041547/
https://www.ncbi.nlm.nih.gov/pubmed/21347143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041547/
https://www.ncbi.nlm.nih.gov/pubmed/21347143

Ejemplares similares