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GC content around splice sites affects splicing through pre-mRNA secondary structures

BACKGROUND: Alternative splicing increases protein diversity by generating multiple transcript isoforms from a single gene through different combinations of exons or through different selections of splice sites. It has been reported that RNA secondary structures are involved in alternative splicing....

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Kuo, CC Jay, Chen, Liang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041747/
https://www.ncbi.nlm.nih.gov/pubmed/21281513
http://dx.doi.org/10.1186/1471-2164-12-90