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Protective Effector Memory CD4 T Cells Depend on ICOS for Survival

Memory CD4 T cells play a vital role in protection against re-infection by pathogens as diverse as helminthes or influenza viruses. Inducible costimulator (ICOS) is highly expressed on memory CD4 T cells and has been shown to augment proliferation and survival of activated CD4 T cells. However, the...

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Detalles Bibliográficos
Autores principales: Moore, Tamson V., Clay, Bryan S., Ferreira, Caroline M., Williams, Jesse W., Rogozinska, Magdalena, Cannon, Judy L., Shilling, Rebecca A., Marzo, Amanda L., Sperling, Anne I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041765/
https://www.ncbi.nlm.nih.gov/pubmed/21364749
http://dx.doi.org/10.1371/journal.pone.0016529