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PLP2 of Mouse Hepatitis Virus A59 (MHV-A59) Targets TBK1 to Negatively Regulate Cellular Type I Interferon Signaling Pathway
BACKGROUND: Coronaviruses such as severe acute respiratory syndrome (SARS) coronavirus (SCoV) and mouse hepatitis virus A59 (MHV-A59) have evolved strategies to disable the innate immune system for productive replication and spread of infection. We have previously shown that papain-like protease dom...
Autores principales: | Wang, Gang, Chen, Gang, Zheng, Dahai, Cheng, Genhong, Tang, Hong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041802/ https://www.ncbi.nlm.nih.gov/pubmed/21364999 http://dx.doi.org/10.1371/journal.pone.0017192 |
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