A set of aspartyl protease-deficient strains for improved expression of heterologous proteins in Kluyveromyces lactis

Secretion of recombinant proteins is a common strategy for heterologous protein expression using the yeast Kluyveromyces lactis. However, a common problem is degradation of a target recombinant protein by secretory pathway aspartyl proteases. In this study, we identified five putative pfam00026 aspa...

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Detalles Bibliográficos
Autores principales: Ganatra, Mehul B, Vainauskas, Saulius, Hong, Julia M, Taylor, Troy E, Denson, John-Paul M, Esposito, Dominic, Read, Jeremiah D, Schmeisser, Hana, Zoon, Kathryn C, Hartley, James L, Taron, Christopher H
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041862/
https://www.ncbi.nlm.nih.gov/pubmed/21166768
http://dx.doi.org/10.1111/j.1567-1364.2010.00703.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041862/
https://www.ncbi.nlm.nih.gov/pubmed/21166768
http://dx.doi.org/10.1111/j.1567-1364.2010.00703.x

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