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A set of aspartyl protease-deficient strains for improved expression of heterologous proteins in Kluyveromyces lactis
Secretion of recombinant proteins is a common strategy for heterologous protein expression using the yeast Kluyveromyces lactis. However, a common problem is degradation of a target recombinant protein by secretory pathway aspartyl proteases. In this study, we identified five putative pfam00026 aspa...
Autores principales: | Ganatra, Mehul B, Vainauskas, Saulius, Hong, Julia M, Taylor, Troy E, Denson, John-Paul M, Esposito, Dominic, Read, Jeremiah D, Schmeisser, Hana, Zoon, Kathryn C, Hartley, James L, Taron, Christopher H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041862/ https://www.ncbi.nlm.nih.gov/pubmed/21166768 http://dx.doi.org/10.1111/j.1567-1364.2010.00703.x |
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