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Phencyclidine (PCP)-Induced Disruption in Cognitive Performance is Gender-Specific and Associated with a Reduction in Brain-Derived Neurotrophic Factor (BDNF) in Specific Regions of the Female Rat Brain

Phencyclidine (PCP), used to mimic certain aspects of schizophrenia, induces sexually dimorphic, cognitive deficits in rats. In this study, the effects of sub-chronic PCP on expression of brain-derived neurotrophic factor (BDNF), a neurotrophic factor implicated in the pathogenesis of schizophrenia,...

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Detalles Bibliográficos
Autores principales: Snigdha, Shikha, Neill, Joanna C., McLean, Samantha L., Shemar, Gaurav K., Cruise, Leonie, Shahid, Mohammed, Henry, Brian
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041899/
https://www.ncbi.nlm.nih.gov/pubmed/20852970
http://dx.doi.org/10.1007/s12031-010-9447-5