CLU blocks HDACI-mediated killing of neuroblastoma

Clusterin is a ubiquitously expressed glycoprotein with multiple binding partners including IL-6, Ku70, and Bax. Clusterin blocks apoptosis by binding to activated Bax and sequestering it in the cytoplasm, thereby preventing Bax from entering mitochondria, releasing cytochrome c, and triggering apop...

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Detalles Bibliográficos
Autores principales: Subramanian, Chitra, Jarzembowski, Jason A., Halsey, Sonja M., Kuick, Rork, Opipari, Anthony W., Castle, Valerie P., Kwok, Roland P. S.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041908/
https://www.ncbi.nlm.nih.gov/pubmed/21042904
http://dx.doi.org/10.1007/s13277-010-0120-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041908/
https://www.ncbi.nlm.nih.gov/pubmed/21042904
http://dx.doi.org/10.1007/s13277-010-0120-y

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