Comparison of Pharmacological Modulation of APP Metabolism in Primary Chicken Telencephalic Neurons and in a Human Neuroglioma Cell Line

Sequential cleavage of amyloid precursor protein (APP) by β- and γ-secretases and the formation of Aβ peptides are pivotal for Alzheimer's disease. Therefore, a large number of drugs has been developed targeting APP metabolism. However, many pharmacological compounds have been identified in vit...

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Detalles Bibliográficos
Autores principales: Czvitkovich, Stefan, Duller, Stephan, Mathiesen, Else, Lorenzoni, Klaus, Imbimbo, Bruno P., Hutter-Paier, Birgit, Windisch, Manfred, Wronski, Robert
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041911/
https://www.ncbi.nlm.nih.gov/pubmed/20603724
http://dx.doi.org/10.1007/s12031-010-9416-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041911/
https://www.ncbi.nlm.nih.gov/pubmed/20603724
http://dx.doi.org/10.1007/s12031-010-9416-z

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