PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity

Activity-dependent remodelling of dendritic spines is essential for neural circuit development and synaptic plasticity, but the precise molecular mechanisms that regulate this process are unclear. Activators of Arp2/3-mediated actin polymerisation are required for spine enlargement; however, during...

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Detalles Bibliográficos
Autores principales: Nakamura, Yasuko, Wood, Catherine L, Patton, Andrew P, Jaafari, Nadia, Henley, Jeremy M, Mellor, Jack R, Hanley, Jonathan G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041953/
https://www.ncbi.nlm.nih.gov/pubmed/21252856
http://dx.doi.org/10.1038/emboj.2010.357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041953/
https://www.ncbi.nlm.nih.gov/pubmed/21252856
http://dx.doi.org/10.1038/emboj.2010.357

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