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PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity
Activity-dependent remodelling of dendritic spines is essential for neural circuit development and synaptic plasticity, but the precise molecular mechanisms that regulate this process are unclear. Activators of Arp2/3-mediated actin polymerisation are required for spine enlargement; however, during...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041953/ https://www.ncbi.nlm.nih.gov/pubmed/21252856 http://dx.doi.org/10.1038/emboj.2010.357 |