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Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach
BACKGROUND: Interferon-gamma (IFNγ) is a multifunctional cytokine with antifibrotic and antiproliferative efficiency. We previously found that pancreatic stellate cells (PSC), the main effector cells in cancer-associated fibrosis, are targets of IFNγ action in the pancreas. Applying a combined exper...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042009/ https://www.ncbi.nlm.nih.gov/pubmed/21310022 http://dx.doi.org/10.1186/1476-4598-10-13 |