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Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor

Mammals possess multiple insulin-like growth factor (IGF) binding proteins (IGFBPs), and related proteins, that modulate the activity of insulin/IGF signalling (IIS), a conserved neuroendocrine signalling pathway that affects animal lifespan. Here, we examine if increased levels of an IGFBP-like pro...

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Detalles Bibliográficos
Autores principales: Alic, Nazif, Hoddinott, Matthew P, Vinti, Giovanna, Partridge, Linda
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042147/
https://www.ncbi.nlm.nih.gov/pubmed/21108726
http://dx.doi.org/10.1111/j.1474-9726.2010.00653.x