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Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor
Mammals possess multiple insulin-like growth factor (IGF) binding proteins (IGFBPs), and related proteins, that modulate the activity of insulin/IGF signalling (IIS), a conserved neuroendocrine signalling pathway that affects animal lifespan. Here, we examine if increased levels of an IGFBP-like pro...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042147/ https://www.ncbi.nlm.nih.gov/pubmed/21108726 http://dx.doi.org/10.1111/j.1474-9726.2010.00653.x |