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Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide

BACKGROUND: Eukaryotic translation initiation factor 4G (eIF4G) is thought to influence the translational efficiencies of cellular mRNAs by its roles in forming an eIF4F-mRNA-PABP mRNP that is competent for attachment of the 43S preinitiation complex, and in scanning through structured 5' UTR s...

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Detalles Bibliográficos
Autores principales: Park, Eun-Hee, Zhang, Fan, Warringer, Jonas, Sunnerhagen, Per, Hinnebusch, Alan G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042410/
https://www.ncbi.nlm.nih.gov/pubmed/21269496
http://dx.doi.org/10.1186/1471-2164-12-68