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Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions
BACKGROUND: PH domains represent one of the most common domains in the human proteome. These domains are recognized as important mediators of protein-phosphoinositide and protein-protein interactions. Phosphoinositides are lipid components of the membrane that function as signaling molecules by targ...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042905/ https://www.ncbi.nlm.nih.gov/pubmed/21310079 http://dx.doi.org/10.1186/1472-6807-11-11 |