Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling

BACKGROUND: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable a certain score is observed by pure chance. Asymptotic theories for such questions are available for two random i.i.d. s...

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Detalles Bibliográficos
Autores principales: Wolfsheimer, Stefan, Herms, Inke, Rahmann, Sven, Hartmann, Alexander K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042914/
https://www.ncbi.nlm.nih.gov/pubmed/21291566
http://dx.doi.org/10.1186/1471-2105-12-47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042914/
https://www.ncbi.nlm.nih.gov/pubmed/21291566
http://dx.doi.org/10.1186/1471-2105-12-47

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