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Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6

BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) is an essential mechanism of the lung that matches blood perfusion to alveolar ventilation to optimize gas exchange. Recently we have demonstrated that acute but not sustained HPV is critically dependent on the classical transient receptor potenti...

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Detalles Bibliográficos
Autores principales: Fuchs, Beate, Rupp, Markus, Ghofrani, Hossein A, Schermuly, Ralph T, Seeger, Werner, Grimminger, Friedrich, Gudermann, Thomas, Dietrich, Alexander, Weissmann, Norbert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042943/
https://www.ncbi.nlm.nih.gov/pubmed/21294865
http://dx.doi.org/10.1186/1465-9921-12-20